Artikel Ilmiah
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Anti-inflammatory effect of ethyl acetate fraction of galing plant extract (Cayratia trifolia) on male wistar rats induced by carrageenan
- Artikel Ilmiah
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- 01/04/2019
Abstract Inflammation (inflammation) is a local reaction from living tissue or cells to an excitatory or injury. This study aims to determine the anti-inflammatory activity of ethyl acetate fraction of galling plant extract (Cayratia trifolia) on one of the inflammatory parameters, namely swelling in the legs of rat with 1% carrageenan induction. In addition, this study also aims to determine the effective dose of ethyl acetate fraction of galing plant extract (Cayratia trifolia) as anti-inflammatory. This study used 25 male wistar rats divided into 5 groups. Group 1 (negative control) Na CMC 0.5%, group 2 (positive control) diclofenac sodium 0.0065 mg/gBW rats, and group 3, 4 and 5 suspension ethyl acetate fractions of galing plant extract 0.0065; 0.013 and 0.026 mg/gBB rats.
Anthropometry-based Body Fat Percentage Predicts High hs-CRP in Chronic Kidney Disease Patients
- Artikel Ilmiah
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- 31/03/2019
BACKGROUND: Obesity is an important cardiovascular risk factor and associated with low grade inflammation in chronic kidney disease (CKD) patients. This study aims to assess the association between body fat with serum high sensitivity C-reactive protein (hs-CRP) level in CKD patients. METHODS: A cross-sectional study was performed in 71 CKD patients. Anthropometric measurements included body weight, height, body mass index (BMI), body fat percentage (BFP), skinfold thickness (SKF) of triceps and biceps were performed by trained physician. BFP was calculated using Kwok’s Formula and hs-CRP was measured by Particle enhanced Turbidimetry.
Could Complete Blood Count Parameters and Non-fasting Cholesterol Profile Describe Inflammation and Oxidative Stress in Chronic Kidney Disease?
- Artikel Ilmiah
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- 13/01/2019
BACKGROUND: Establishment of inexpensive clinical laboratory tests to evaluate inflammation and oxidative stress is urgently needed in the limited resources settings. This study aims to investigate the potential of complete blood count (CBC) parameters and non-fasting cholesterol profile parameters to describe inflammation and oxidative stress in chronic kidney disease (CKD) patients. METHODS: Measurement of CBC, non-fasting cholesterol profile, high sensitivity C-reactive protein (hs-CRP) and malondialdehyde (MDA) were performed in 71 CKD patients grouped into hemodialysis (HD) and non-hemodialysis (non-HD). Correlation analysis were performed to assess the potential of CBC and cholesterol profile to describe the level of hs-CRP and MDA.
The Effect of a Low Protein Diet on the Expression of IL-6, TNF-α and TGF-β in the Kidney Tissue of Mice Model
- Artikel Ilmiah
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- 11/01/2019
ABSTRACT Introduction: High prevalence of malnutrition has impact that often causes problems in body organs. Various reports suggest an association between malnutrition and chronic kidney failure. However, the effect of malnutrition on the immunological status of the kidney has not been identified. Objective: to identify the effect malnutrition on the immunological status of the kidney.
Statin Pada Penyakit Ginjal Kronik
- Artikel Ilmiah
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- 13/05/2017
PENDAHULUAN Penyakit Ginjal Kronik (PGK), yang ditandai dengan kelainan fungsi ginjal atau albuminuria selama setidaknya 3 bulan, berhubungan dengan peningkatan risiko penyakit kardiovaskular (PKV). PGK seringkali merupakan komplikasi dari hipertensi dan diabetes, dimana keduanya merupakan faktor risiko PKV.