#Urinary Tract Infection

Thromboembolic involvement and its possible pathogenesis in COVID-19 mortality: lesson from post-mortem reports

Abstract. – The emergence of Coronavirus Disease 19 (COVID-19) as a pandemic has claimed hundreds of thousands of lives worldwide since its initial breakout. With increasing reports from clinical observations and autopsy findings, it became clear that the disease causes acute respiratory distress syndrome (ARDS), as well as a broad spectrum of systemic and multiorgan pathologies, including angiopathy, endothelialitis, and thrombosis. Coagulopathy is associated with the activity of megakaryocytes, which play crucial roles in modulating the platelet homeostasis. Only a few autopsy reports include findings on thrombosis formation and the presence of megakaryocytes. Here we review and summarize the possible involvement and the pathophysiology of the thromboembolic events in COVID-19 patients based on post-mortem reports. We reviewed post-mortem reports from March 2020 to September 2020.

Urinary Tract Infection

Rumah Ginjal - PENDAHULUAN Infeksi saluran kemih (ISK) merupakan penyakit yang paling umum dijumpai dalam praktek kedokteran. Sekitar 20 – 40% wanita usia 20 – 40 tahun di Amerika Serikat mengalami ISK. ISK terjadi pada lebih dari 6 juta kunjungan ke praktik dokter per tahun di Amerika Serikat, seperlimanya merupakan kunjungan ke unit gawat darurat. Di Amerika, keadaan ini menyebabkan sekitar tujuh juta orang berkunjung ke dokter dan sekitar satu juta harus menjalani rawat inap tiap tahun. Sebagian besar kunjungan disebabkan oleh sistitis akut, sedangkan pyelonefritis akut dan abses perinefrik menempati porsi yang lebih kecil (Foxman, 2002).